Fashion designer Anita and computer-game writer Roger meet, fall in love and marry along with their dalmatians Perdita and Pongo. But the proud dogs' puppies are kidnapped by Anita's boss Cruella De Vil, who is stealing young dalmatians to make the coat she has set her heart on. Enlisting the help of the British animal kingdom, Pongo and Perdita set out to find and rescue all ninety-nine pups from their fearsome captors, Jasper and Horace. 101斑点狗，超赞动画真人版人版。感动啊。狗狗的旧事。观影后感。快乐弥漫。温馨的童话。好多狗。找电影。好多漂亮的狗狗。 一天，罗杰（杰夫•丹尼尔斯 Jeff Daniels 饰）和安妮（朱莉•理查德森 Joely Richardson 饰）塔所养的斑点狗在和主人散步时一见钟情，罗杰和安妮塔也因此走到了一起。不久，两只斑点狗就生了一窝小狗。一家人生活得十分开心。 这时，安妮塔的变态老板想用斑点狗皮做一件皮衣，在遭到了罗杰和安妮塔的拒绝后，她派人掳走了这窝小狗。罗杰夫妇一早醒来发现小狗不见了，急切里四出寻找，然而音讯全无。两人的爱犬这时按捺不住，在动物朋友们的帮助下，独自前往了虎穴……
