During the COVID-19 pandemic, the staff of Chastain does their best to treat the overwhelming number of patients that they face while also trying to protect their loved ones; Conrad and Nic get married. FOX的《#驻院医生# The Resident》已续订第四季,而主创之一Amy Holden Jones表示,剧集新季中新型冠状病毒会占据剧情主要部份,第四季首播将聚焦在疫情爆发的初期,并会描述医护人员面临的各种危险。